Research Interests:
Physical Chemistry; molecular spectroscopy and modeling, NMR spectroscopy of peptides and antibiotics, laboratory automation.
Outside Interests:
Boy Scout Leader (Woodbadge Course Director), uniformed volunteer for the
U.S. Forest Service with an emphasis on trail construction and maintenance, hiking
and cross-country skiing, member of the Pomona College Choir
Recent Publications:
Steinmetz, W. E.;
Shapiro, B. L.*; Roberts, J. J.*; “The Structure of Erythromycin Enol Ether as a Model for its Activity as a Motilide”, J.
Med. Chem., in press.
Kohlmann, O.; Steinmetz, W. E.; Mao, X.-A.; Wuelfing, W. P.; Templeton, A. C.; Murray, R. W.; Johnson,
C. S., Jr.; “NMR Diffusion, Relaxation, and Spectroscopic Studies of
Water Soluble, Monolayer Protected Gold Nanoclusters”,
J. Phys. Chem.B,
2001, 105, 8801-8809.
Blackwell, H. E.; Sadowsky, J. D.*; Howard, R. J.; Sampson, J. N.; Chao, J. A.; Steinmetz, W. E.; O’Leary, D. J.;
Grubbs, R. H.; “Ring-closing Metathesis of Olefinic
Peptides: Design, Synthesis, and Structural Characterization of Macrocyclic Helical Peptides”, J. Org. Chem., 2001, 66,
5291-5302.
Steinmetz, W. E., Sadowsky, J. D.*; Rice, J. S.*; Roberts, J. J.*; Bui, Y. K.*; “Determination of the Aqueous-phase Structure of 6-O-Methylerythromycin from NMR Constraints”, Magn. Reson. Chem., 2001, 39, 163-172.
Steinmetz, W.E.;"A CoMFA Model of Steric and Electronic Effects of Phosphorous Ligands", Quant. Struct. Act.Relat. 1996, 15, 1-6.
Steinmetz, W.E.;"A CoMFA Analysis of Selected Physical Properties of Amino Acids in Water", Quant. Struct. Act.Relat. 1995, 14, 19-23.
Steinmetz, W.E.; Bianco, T. I.*; Zollinger, M.*; Pesiri, D.*"Characterization of Multiple Forms of Mast Cell Degranulating Peptide by NMR Spectroscopy", PeptideResearch 1994, 7, 77-82.
*, undergraduate research participants in the laboratory of WES.
.