Director of Molecular Biology




Research Interest: The study ofgenome maintenance mechanisms in particular DNA recombinationbetween short homologous sequences and how it can affect genomeinstability.




Negritto, M. C, Qiu, J., Ratay, D.O.,Shen, B. and Bailis A. M. A novel function of Rad27 (FEN-1) inrestricting shrot Ùsequence recombination. Mol Cell. Biol. 21,2349-2358. (2001).


Maines, S., Negritto, M.C., Wu, X.,Manthey, G.M. and Bailis, A. M.  Novel mutations in the RAD3and SSL1 genes perturb genome stability by stimulatingrecombination between short-repeats in Saccharomycescerevisiae. Genetics 150 (3), 963-976. (1998).


Negritto, M. C., Wu, X., Kuo, T.,Chu, S and Bailis, A. M. Influence of DNA sequence identity onefficiency of targeted gene replacement. Moll. Cell. Biol. 17,278-286. (1997).


Bailis, A. M., Maines, S. and Negritto,M.C. The essential helicase gene RAD3 suppressesshort-sequence recombination in Saccharomyces cerevisiae.Mol. Cell. Biol. 15, 3998-4008. (1995).