MARIA CRISTINA (Tina) NEGRITTO

Director of Molecular Biology

• Licenciatura in Biology. (Equivalent to a Master's degree). School of Hard Sciences, University of Buenos Aires (UBA). Buenos Aires, Argentina

• Ph. D., Beckman Research Institute of the City of Hope National Medical Center (BRI-COH). Duarte, CA.

Research Interest: The study ofgenome maintenance mechanisms in particular DNA recombinationbetween short homologous sequences and how it can affect genomeinstability.

PUBLICATIONS

Negritto, M. C, Qiu, J., Ratay, D.O.,Shen, B. and Bailis A. M. A novel function of Rad27 (FEN-1) inrestricting shrot Ùsequence recombination. Mol Cell. Biol. 21,2349-2358. (2001).

Maines, S., Negritto, M.C., Wu, X.,Manthey, G.M. and Bailis, A. M.  Novel mutations in the RAD3and SSL1 genes perturb genome stability by stimulatingrecombination between short-repeats in Saccharomycescerevisiae. Genetics 150 (3), 963-976. (1998).

Negritto, M. C., Wu, X., Kuo, T.,Chu, S and Bailis, A. M. Influence of DNA sequence identity onefficiency of targeted gene replacement. Moll. Cell. Biol. 17,278-286. (1997).

Bailis, A. M., Maines, S. and Negritto,M.C. The essential helicase gene RAD3 suppressesshort-sequence recombination in Saccharomyces cerevisiae.Mol. Cell. Biol. 15, 3998-4008. (1995).